Suramin sodium is a Medicine belongs to Antiprotozoals group whose information about Brand can be referenced from   Book : Martindale    Page : 936   Edition : 37,

  ►   Brandname : Germanin

  ►  Strength : Injection with nf  ,

Reference of this Medicine for its Strength can be taken from   Book : Martindale    Page :    Edition : ,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : IV,
Reference :-   Book : Martindale    Page : 936   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Early-stage trypanosomiasis IV 5 mg/kg Injection For one day.

Ref :-  Book : Martindale    Page : 936   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Early-stage trypanosomiasis IV 5 mg/kg Injection
2 Early-stage trypanosomiasis IV 10 mg/kg Injection
3 Early-stage trypanosomiasis IV 20 mg/kg Injection

Ref :- Book : Martindale    Page : 936   Edition : 37,
►  Side Effect : paraesthesia, skin eruptions, blood dyscrasias, fever, polyuria, raised liver enzyme values, fatigue, photophobia, lachrymation, proteinuria, nausea, vomiting, shock, seizure, loss of consciousness, abdominal pain, mouth ulcers, Skin reactions, urticarial, pruritus, haematuria, hyperaesthesia of the palms and soles, increased thirst, adrenal insufficiency, casts in the urine,
Ref :-   Book : Martindale    Page : 935   Edition : 37,

►  Drug Interaction : Drug interaction of Suramin sodium is with NA

  ►    Mechanism of Drug Drug Interaction :  nf,
Ref :-   Book :    Page :    Edition : ,


►  Contraindication : hepatic disease, Hypersensitivity, renal disease,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 935   Edition : 37,
  ►  Mechanism of Action :   Suramin is a relatively slowly acting trypanocide (>6 hours in vitro) with high clinical activity against both T. b. gambiense and T. b. rhodesiense. Its mechanism of action is unknown. ,
Ref :-   Book : Goodman    Page : 1447   Edition : 12,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Renal,
Ref :-   Book : Basic & Clinical pharmacology    Page : 933   Edition : 12,


►    Plasma Half-life :
  Min value :-   1200 hours,    Max value :-   NA
Ref :-   Book : Martindale    Page :    Edition : ,

►    Peak Plasma Concentration :   Min value :-   several weeks,    Max value :-   NA
Ref :-   Book : Martindale    Page : 935   Edition : 37,