Suxamethonium/Succinylcholinechloride (Suxamethonium chloride) is a Medicine belongs to Neuromuscular blocker group whose information about Brand can be referenced from   Book : Martindale    Page : 2076   Edition : 37,

  ►   Brandname : Midarine,Anectine,Quelicin

  ►  Strength : Injection with 25  mg/ml, Injection with 50  mg/ml, Injection with 100  mg/ml, Injection with 500  mg, Injection with 1000  mg,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 481   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : IV,
Reference :-   Book : Martindale    Page : 2076   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info

Ref :-  Book :




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : Apnoea, tachyphylaxis, Transient fasciculations, rhabdomyolysis, myoglobinemia, myoglobinuria, increase in gastric secretion, increase in bronchial secretion, increase in salivary secretion,
Ref :-   Book : Martindale    Page : 2073   Edition : 37,

►  Drug Interaction : Drug interaction of Suxamethonium/Succinylcholinechloride (Suxamethonium chloride) is with Echothiophate Iodide , Edrophonium, Neostigmine , Pyridostigmine , Rivastigmine , Tacrine , Phenytoin , Cyclophosphamide , Halothane , Propofol , Fentanyl, Procaine, Cocaine , Chloroprocaine, liraglutide , Metoclopramide , Bambuterol,
Ref :-   Book : Martindale    Page : 2066.1,2073.2   Edition : 37,


  ►    Mechanism of Drug Drug Interaction :  Local anesthetics :Lidocaine, procainamide, quinidine, and verapamil all have some neuromuscular blocking activity and may enhance the block produced by neuromuscular blockers. .2 Some antibacterials in very high concentration can produce a muscle paralysis that may be additive to or synergistic with that produced by neuromuscular blockers.3. Anticholinesterases, including ecothiopate, edrophonium, galantamine, neostigmine, pyridostigmine, rivastigmine, and possibly donepezil, antagonise the effect of competitive neuromuscular blockers.,
Ref :-   Book : Martindale    Page : 2066,2073   Edition : 37,


►  Contraindication : pregnancy, burns, massive trauma, renal impairment, Sepsis, hyperkalaemia, Hypersensitivity,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 2074   Edition : 37,
  ►  Mechanism of Action :   It combines with cholinergic receptors of the motor end-plate to produce depolarization but is resistant to breakdown by acetylcholinesterase. This prevents repolarization and subsequent depolarization, and a flaccid muscle paralysis occurs.,
Ref :-   Book : Martindale    Page : 2075   Edition : 37,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Renal,
Ref :-   Book : Clinical Pharmacology    Page : 357   Edition : 9,


►    Plasma Half-life :
  Min value :-   016 hours,    Max value :-   NA
Ref :-   Book : Clinical Pharmacology    Page : 357   Edition : 9,

►    Peak Plasma Concentration :   Min value :-   nf,    Max value :-   NA
Ref :-   Book :    Page :    Edition : ,