Tamsulosin is a Medicine belongs to Adrenoceptor blockers group whose information about Brand can be referenced from   Book : Martindale    Page : 2402   Edition : 37,

  ►   Brandname : Urimax,Flomax,Bazetham,Contiflo

  ►  Strength : Capsule with 0.4  mg,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 166   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Martindale    Page : 2401   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Benign prostatic hyperplasia Oral 400 micrograms Capsule o.d.

Ref :-  Book : Martindale    Page : 2401   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : Dizziness, drowsiness, headache, lack of energy, palpitations, oedema, nausea, chest pain, dyspnoea, constipation, diarrhea, vomiting, Depression, Nervousness, Sleep disturbances, vertigo, hallucinations, paraesthesia, nasal congestion, epistaxis, dry mouth, urinary frequency, incontinence, reddened sclera, Blurred Vision, tinnitus, abnormal liver enzyme values, Pancreatitis, arthralgia, alopecia, lichen planus, Skin rashes, pruritus, diaphoresis,
Ref :-   Book : Martindale    Page : 1510   Edition : 37,

►  Drug Interaction : Drug interaction of Tamsulosin is with Tenecteplase , Zonisamide , Warfarin , Diclofenac , Furosemide ,
Ref :-   Book : Martindale    Page : 1510, 2401   Edition : 37,


  ►    Mechanism of Drug Drug Interaction :  The hypotensive effects of prazosin may be enhanced by use with diuretics and other antihypertensives, and by alcohol and other drugs that cause hypotension. The risk of first-dose hypotension may be particularly increased in patients receiving beta blockers or calcium channel blockers. Tamsulosin is metabolized by cytochrome P450 isoenzymes CYP2D6 and CYP3A4, and inhibitors of these isoenzymes may increase exposure to Tamsulosin. It should not be usedstrong inhibitors of CYP3A4; caution is required when giving Tamsulosin with a moderate inhibitor of CYP3A4, with strong or moderate inhibitor of CYP2D6, or in patients who are CYP2D6 poor metabolisers, particularly at oral Tamsulosin doses higher than 400 micrograms daily. Tamsulosin is given with warfarin or diclofenac as the elimination of Tamsulosin may be increased and therefore the exposure redused. Furosemide may also reduce exposure, but Tamsulosin concentration remain with in the normal range.,
Ref :-   Book : Martindale    Page : 1510,2401   Edition : 37,


►  Contraindication : hepatic impairment,
Ref :-   Book : Martindale    Page : 2401   Edition : 37,
  ►  Mechanism of Action :   Block endogenous catecholamines from binding to α1- and α2 – adrenoceptors, causing vasodilation, decreased blood pressure, and decreased peripheral resistance.,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 145   Edition : 3,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Soya with Another pathway, Clove with Another pathway,

  ►  Pathway with its reference as follows :-
  • Isoflavonones is Helpful in treating BPH --- (PDR for herbal medicine. (2016) (4th ed.). Thomson Reuters, 2007. )
  • Isoflavonones is Helpful in treating BPH --- (Duke, J. (2002). Hand Book Of Medicinal Herbs (2nd ed.). United States Of America: CRC Press. )

  •   ►  URL -- http://www.travolekar.ru/arch/Pdr_for_Herbal_Medicines.pdf, https://books.google.co.in/books?id=B_XLBQAAQBAJ&pg=PP5&lpg=PP5&dq=Duke, +J.+(2002).+Hand+Book+Of+Medicinal+Herbs+(2nd+ed.).+United+States+Of+America:+CRC+,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Hepatic (Metabolism), Renal,
    Ref :-   Book : Martindale    Page : 2401   Edition : 37,


    ►    Plasma Half-life :
      Min value :-   4 hours,    Max value :-   5 hours,
    Ref :-   Book : Martindale    Page : 2401   Edition : 37,

    ►    Peak Plasma Concentration :   Min value :-   1 hour,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 2401   Edition : 37,