Telavancin is a Medicine belongs to Antibacterials group whose information about Brand can be referenced from   Book : Martindale    Page : 371   Edition : 38,

  ►   Brandname : Vibativ

  ►  Strength : Injection with 0.25  gm, Injection with 0.75  gm,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 808   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : IV infusion,
Reference :-   Book : Martindale    Page : 371   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Antibacterial IV infusion 10 mg/kg Injection
2 If weight is 30% or more over ideal BW, dose using adjusted BW as for aminoglycoside. Ref: The Sanford Guide To Antimicrobial Therapy, pg 232.

Ref :-  Book : Martindale    Page : 371   Edition : 38,    Page :    Edition : ,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : transient taste disturbance, mild nausea, Infusion-related reaction so-called ‘red-neck’ or ‘red-man’ syndrome, nephrotoxicity,
Ref :-   Book : Martindale    Page : 371   Edition : 38,

►  Drug Interaction : Drug interaction of Telavancin is with NSAIDS, Angiotensin conveting enzyme inhibitors , Loop Diuretics ,  NA

  ►    Mechanism of Drug Drug Interaction :  Risk of renal toxicity with telavancin is increased in patients using other drugs known to affect kidney function (including NSAIDs, ACE inhibitors, and loop diuretics). Because telavancin may prolong the QT interval, it should be used with caution in patients taking other drugs known to have this effects.,
Ref :-   Book : Martindale    Page : 371   Edition : 38,


►  Contraindication : congenital long QT syndrome, Known prolongation of the QT-interval, uncompensated heart failure, Severe left ventricular hypertrophy,
Ref :-   Book : Martindale    Page : 371   Edition : 38,
  ►  Mechanism of Action :   Inhibits cell wall synthesis by binding to the D-Ala-D-Ala terminus of nascent peptidoglycan,
Ref :-   Book : Basic & Clinical pharmacology    Page : 806   Edition : 12,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Renal,
Ref :-   Book : Martindale    Page : 371   Edition : 38,


►    Plasma Half-life :
  Min value :-   8 hours,    Max value :-   NA
Ref :-   Book : Martindale    Page : 371   Edition : 38,

►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA