Terazosin is a Medicine belongs to Alpha1 Selective Adrenoceptor Blockers group whose information about Brand can be referenced from   Book : Martindale    Page : 1548   Edition : 37  

  ►   Brandname : Olyster, Zytrin, Hytrin
  ►  Strength : Capsule with 1 mg.  Capsule with 2 mg.  Capsule with 5 mg.  Capsule with 10 mg.  Tablet with 1 mg.  Tablet with 2 mg.  Tablet with 5 mg.  Tablet with 10 mg. 

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 189   Edition : 12  
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral
Reference :-   Book : Martindale    Page : 1548   Edition : 37  

Dosing of Medicine differ in Adult & Pediatrics ↓

Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 hypertension Oral 1 mg Tablet/Capsule h.s. Dose increasing gradually at intervals of 7 days according to the patient’s response. Hypertension the usual maintenance dose is 2 to 10 mg once daily and the usual maximum dose is 20 mg daily in a single dose or two divided doses.
2 Benign prostatic hyperplasia Oral 1 mg Tablet/Capsule h.s. Dose increasing gradually at intervals of 7 days according to the patient’s response. The usual maintenance dose is 5 to 10 mg once daily

Ref :-  Book : Martindale    Page : 1548   Edition : 37  



Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 hypertension Oral 1 mg/day Tablet/Capsule o.d.

Ref :- Book : Nelson's textbook of Pediatrics    Page : 1645   Edition : 19  
►  Side Effect : Orthostatic hypotension, Dizziness, Drowsiness, Headache, Lack of energy, Nausea, palpitations, Oedema, Chest pain, Dyspnoea, Constipation, Diarrhoea, Vomiting, Depression, Nervousness, Sleep disturbances, Vertigo, Hallucinations, Paresthesia, Nasal congestion, Epistaxis, Dry mouth, Urinary frequency, Urinary incontinence, Reddened sclera, Blurred Vision, Tinnitus, Abnormal liver enzyme values, Pancreatitis, Arthralgia, Alopecia, Lichen planus, Skin rashes, pruritus, Diaphoresis, impotence, Priapism
Ref :-   Book : Martindale    Page : 1510,1548   Edition : 37.  

►  Drug Interaction : Drug interaction of Terazosin is with Diuretics, , Alcohol,  NA

  ►    Mechanism of Drug Drug Interaction :  The hypotensive effects of Terazosin may be enhanced by use with diuretics and other antihypertensives, and by alcohol and other drugs that cause hypotension. The risk of first-dose hypotension may be particularly increased in patients receiving beta blockers or calcium channel blockers
Ref :-   Book : Martindale    Page : 1510,1548   Edition : 37.  


►  Contraindication : Hepatic impairment, Renal impairment, Prazosin is not recommended for the treatment of heart failure caused by mechanical obstruction, for example aortic or mitral valve stenosis, pulmonary embolism, and restrictive pericardial disease., It should be used with caution in patients with angina pectoris. Prazosin may cause drowsiness or dizziness; patients so affected should not drive or operate machinery.
Ref :-   Book : Martindale    Page : 1510,1548   Edition : 37.  
  ►  Mechanism of Action :   Block endogenous catecholamines from binding to α1- adrenoceptors, causing vasodilation, decreased blood pressure, and decreased peripheral resistance.
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 145   Edition : 3.  

Pathway of DIETARY Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Celery with Another pathway.  

  ►  Pathway with its reference as follows :-
  • High water content act as vasoliater --- (Kokate, c. & Purohit, A. (2016). pharmacognosy. nirali prakashan. )

  •   ►  URL --
  • https://www.sapnaonline.com/books/pharmacognosy-ck-kokate-8196396155-9788196396152 .

  • DIETARY Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication DIETARY Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Hepatic (Metabolism), Biliary, Renal, Faecal
    Ref :-   Book : Martindale    Page : 1548   Edition : 37.  

    ►    Plasma Half-life :   Min value :-   12 hours,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 1548   Edition : 37.  

    ►    Peak Plasma Concentration :   Min value :-   1 hour,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 1548   Edition : 37.