Tetrabenazine is a Medicine belongs to Miscellaneous Drugs group whose information about Brand can be referenced from   Book : Martindale    Page : 2633   Edition : 37,

  ►   Brandname : Xenazine

  ►  Strength : Tablet with 12.5  mg, Tablet with 25  mg,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 498   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Martindale    Page : 2633   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Chorea Oral 25 mg Tablet t.i.d.
2 Ballism Oral 25 mg Tablet t.i.d.
3 Organic CNS movement disorder Oral 25 mg Tablet t.i.d.
4 Huntington's chorea Oral 12.5 mg Tablet Dose: Given daily.
5 Tardive dyskinesia Oral 12.5 mg Tablet Dose: Given daily.

Ref :-  Book : Martindale    Page : 2633   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : Depression, drowsiness, extrapyramidal dysfunction, gastrointestinal disturbance, Neuroleptic malignant syndrome, Orthostatic hypotension, parkinsonism,
Ref :-   Book : Martindale    Page : 2633   Edition : 37,

►  Drug Interaction : Drug interaction of Tetrabenazine is with Levodopa , Reserpine, Acarbose ,
Ref :-   Book : Martindale    Page : 2633   Edition : 37,


  ►    Mechanism of Drug Drug Interaction :  Tetrabenazine has been reported to block the action of reserpine. It may also diminish the effects of levodopa and exacerbate the symptoms of parkinsonism. Use of tetrabenazine immediately after a course of an MAOI may lead to confusion, restlessness, and disorientation; tetrabenazine should not be given with, or within 14 days of stopping, such therapy.,
Ref :-   Book : Martindale    Page : 2633   Edition : 37,


►  Contraindication : Peptic ulceration, hepatic impairment, parkinsonism, Parkinson’s disease, depression,
Ref :-   Book : Martindale    Page : 2633   Edition : 37,
  ►  Mechanism of Action :   nf,
Ref :-   Book :    Page :    Edition : ,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Renal,
Ref :-   Book : Martindale    Page : 2633   Edition : 37,


►    Plasma Half-life :
  Min value :-   NA    Max value :-   NA


►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA