Thyrotrophin is a Medicine belongs to Antithyroid agent group whose information about Brand can be referenced from   Book : Martindale    Page : 2378   Edition : 37,

  ►   Brandname : Thyrogen

  ►  Strength : Injection with 1.1  mg,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 695   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : IM,
Reference :-   Book : Martindale    Page : 2378   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 IM 900 micrograms Injection Dose: Given 24 hours apart.

Ref :-  Book : Martindale    Page : 2378   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1

Ref :- Book :    Page :    Edition : ,
►  Side Effect : nausea, vomiting, headache, desire to micturate, flushing, hypersensitivity reactions, Skin rashes, Urticaria, erythema and swelling at the injection site, anaphylaxis,
Ref :-   Book : Martindale    Page : 2378   Edition : 37,

►  Drug Interaction : Drug interaction of Thyrotrophin is with NA

  ►    Mechanism of Drug Drug Interaction :  N.F.R.B,
Ref :-   Book :    Page :    Edition : ,


►  Contraindication : Thyrotrophin should not be given to patients with recent myocardial infarction or uncorrected adrenocortical insufficiency, including adrenocortical insufficiency secondary to hypopituitarism. Care is also required in patients with cardiovascular disease.,
Ref :-   Book : Martindale    Page : 2378   Edition : 37,
  ►  Mechanism of Action :   Thyrotrophin is a glycoprotein that is secreted by the anterior lobe of the pituitary and has an alpha subunit essentially the same as that of the gonadotrophins. Its main actions are to increase iodine uptake by the thyroid and the formation and secretion of the thyroid hormones.,
Ref :-   Book : Martindale    Page : 2378   Edition : 37,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   NA


►    Plasma Half-life :
  Min value :-   N.F.R.B,    Max value :-   NA
Ref :-   Book :    Page :    Edition : ,

►    Peak Plasma Concentration :   Min value :-   N.F.R.B,    Max value :-   NA
Ref :-   Book :    Page :    Edition : ,