Tinidazole is a Medicine belongs to Antiprotozoals group whose information about Brand can be referenced from   Book : Martindale    Page : 950   Edition : 38,    Page :   Edition : ,

  ►   Brandname : Enidazol,Tiniba,Fasigyn,Tindamax,Ciplox-TZ,h-p kit

  ►  Strength : Tablet with NF  ,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page :    Edition : ,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, parentral, Topical,
Reference :-   Book : Martindale    Page : 949   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Intestinal amoebiasis Oral 2 gm Dose: Given for 2 or 3 days.
2 Hepatic amoebiasis Oral 1.5 2 gm Dose: Given as a single daily dose may be given for 3 days or occasionally up to 6 days.
3 Giardiasis Oral 2 gm o.d.
4 Trichomoniasis Oral 2 gm o.d.
5 Ulcerative gingivitis Oral 2 gm o.d.

Ref :-  Book : Martindale    Page : 949   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Intestinal amoebiasis Oral 50 60 mg/kg
2 Hepatic amoebiasis Oral 50 60 mg/kg
3 Giardiasis Oral 50 75 mg/kg o.d.
4 Trichomoniasis Oral 50 75 mg/kg o.d.

Ref :- Book : Martindale    Page : 949   Edition : 38,
►  Side Effect : nausea, headache, anorexia, Metallic after taste, vomiting, paraesthesia, seizure, peripheral neuropathy,
Ref :-   Book : Harrison's principles of internal medicine    Page : 1680   Edition : 18,

►  Drug Interaction : Drug interaction of Tinidazole is with Warfarin , Phenytoin , Felbamate, Phenobarbital ,
Ref :-   Book : Martindale    Page : 1680   Edition : 37,


  ►    Mechanism of Drug Drug Interaction :  Warfarin: effect may be enhanced by tinidazole. Disulfiram: psychotic reaction. Phenobarbital, phenytoin: may accelerate elimination of tinidazole. Lithium: serum levels may be elevated by tinidazole. Cimetidine: may prolonged half-life of tinidazole,
Ref :-   Book : Harrison's principles of internal medicine    Page : 1680   Edition : 18,


►  Contraindication : First trimester of Pregnancy, peripheral neuropathy, transient epileptiform seizures, leucopenia, hepatic impairment,
Ref :-   Book : Martindale    Page : 939   Edition : 37,
  ►  Mechanism of Action :   In obligate anaerobic microorganisms (but not in aerobes) tinidazole is converted into an active form by reduction of its nitro group: this binds to DNA and prevents nucleic acid formation; it is bacteriostatic. ,
Ref :-   Book : Clinical Pharmacology    Page : 233   Edition : 9,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Eucalyptus oil with ,

  ►  Pathway with its reference as follows :-
  • Eucalyotol have antibiotic effect --- ( Kokate, c. & Purohit, A. (2016). pharmacognosy. nirali prakashan. )

  •   ►  URL -- https://www.sapnaonline.com/books/pharmacognosy-ck-kokate-8196396155-9788196396152,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Fecal, Renal,
    Ref :-   Book : Martindale    Page : 937   Edition : 37,


    ►    Plasma Half-life :
      Min value :-   12 hours,    Max value :-   14 hours,
    Ref :-   Book : Martindale    Page : 937   Edition : 37,

    ►    Peak Plasma Concentration :   Min value :-   2 hours,    Max value :-   NA
    Ref :-   Book :    Page : 937   Edition : 37,