Tioconazole is a Medicine belongs to Antifungal group whose information about Brand can be referenced from   Book : Martindale    Page : 596   Edition : 37, Martindale    Page : 596   Edition : 37,

  ►   Brandname : Trosyl,vagistat-1,Trosyd; Mykontral

  ►  Strength : vaginal ointment with 6.5  %, Pessary with   , cream, lotion, or powder with 1  %, Nail Solution with 28%  w/w,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 858   Edition : 12, Martindale    Page : 596   Edition : 37,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Topical,
Reference :-   Book : Basic & Clinical pharmacology    Page : 858   Edition : 12,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Vaginal candidiasis Vaginal 300 mg Pessaries or vaginal ointment
2 Superficial fungal infections Topical 1 % Cream
3 Superficial fungal infections Topical 1 % Lotion
4 Superficial fungal infections Topical 1 % Powder
5 Nail infections Topical 28% w/w Solution

Ref :-  Book : Martindale    Page : 596   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1

Ref :- Book :    Page :    Edition : ,
►  Side Effect : burning , Itching, erythema, Intravaginal preparations of terconazole may damage latex contraceptives and additional contraceptive measures are therefore necessary during local application.,
Ref :-   Book : Martindale    Page : 596   Edition : 37,

►  Drug Interaction : Drug interaction of Tioconazole is with NA

  ►    Mechanism of Drug Drug Interaction :  N.F.R.B,
Ref :-   Book :    Page :    Edition : ,


►  Contraindication : pregnancy,
Ref :-   Book : Martindale    Page : 596   Edition : 37,
  ►  Mechanism of Action :   Tioconazole interfare with fungal oxidative enzymes to cause lethal accumulation of hydrogen peroxide; they also reduce the formation of ergosterol, an important consitituent of the fungal cell wall which thus becomes permeable to intracellular contituents.,
Ref :-   Book : Clinical Pharmacology    Page : 265   Edition : 19,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   NA


►    Plasma Half-life :
  Min value :-   NA    Max value :-   NA


►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA