Tiopronin is a Medicine belongs to Chelators Antidotes and Antagonists group whose information about Brand can be referenced from   Book : Martindale    Page : 1610   Edition : 37,

  ►   Brandname : Thiola

  ►  Strength : Injection with NF  ,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page :    Edition : ,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, IV, IM,
Reference :-   Book : Martindale    Page : 1609   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Cystinuria Oral 0.8 1 gm Dose: Given daily in divided doses.
2 Rheumatoid arthiritis Oral 0.8 1 gm Dose: Given daily in divided doses.

Ref :-  Book : Martindale    Page : 1609   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : fever,
Ref :-   Book : Martindale    Page : 1578   Edition : 38,

►  Drug Interaction : Drug interaction of Tiopronin is with NA

  ►    Mechanism of Drug Drug Interaction :  nf,
Ref :-   Book :    Page :    Edition : ,


►  Contraindication : lupus erythematosus, agranulocytosis, aplastic anaemia, thrombocytopenia, renal impairment,
Ref :-   Book : Martindale    Page : 1599   Edition : 37,
  ►  Mechanism of Action :   Tiopronin is a chelator that aids the elimination from the body of certain heavy-metal ions, including copper, lead, and mercury, by forming stable soluble complexes with them that are readily excreted by the kidney. ,
Ref :-   Book : Martindale    Page : 1600   Edition : 37,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Cilantro with Another pathway, Garlic with Another pathway, Raw apple with Another pathway, Banana with Another pathway, Grapes with Another pathwayAnother pathway, Grapes with Another pathwayAnother pathway,

  ►  Pathway with its reference as follows :-
  • Natural Chelation --- ( E, M. (2013). Chelation: Harnessing and Enhancing Heavy Metal Detoxification—A Review. The Scientific World Journal. )
  • Garlic-Sulphur compound is a Natural Chelation --- ( Chelation: Harnessing and Enhancing Heavy Metal Detoxification—A Review. The Scientific World Journal. http://dx.doi.org/10.1155/2013/219840 )
  • Raw apples- Malic acid is a Natural Chelation --- ( E, M. (2013). Chelation: Harnessing and Enhancing Heavy Metal Detoxification—A Review. The Scientific World Journal. http://dx.doi.org/10.1155/2013/219840 )
  • Natural Chelation --- ( Y, H. (2010). Radical scavenging and antioxidant activity of tannic acid. Arabian Journal Of Chemistry, 3(1). )
  • Tannic acid act as Natural Chelation --- ( Y, H. (2010). Radical scavenging and antioxidant activity of tannic acid. Arabian Journal Of Chemistry, 3(1). )
  • Tannic acid act as Natural Chelation --- (Y, H. (2010). Radical scavenging and antioxidant activity of tannic acid. Arabian Journal Of Chemistry, 3(1). )
  • Tannic acid act as Natural Chelation --- ( Y, H. (2010). Radical scavenging and antioxidant activity of tannic acid. Arabian Journal Of Chemistry, 3(1). )
  • Tannic acid act as Natural Chelation --- (Y, H. (2010). Radical scavenging and antioxidant activity of tannic acid. Arabian Journal Of Chemistry, 3(1). )

  •   ►  URL -- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654245/, www.ncbi.nlm.nih.gov/pmc/articles/PMC3654245/, http://www.sciencedirect.com/science/article/pii/S187853520900046X,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Renal,
    Ref :-   Book : Martindale    Page : 1609   Edition : 37,


    ►    Plasma Half-life :
      Min value :-   nf,    Max value :-   NA
    Ref :-   Book :    Page :    Edition : ,

    ►    Peak Plasma Concentration :   Min value :-   3 hours,    Max value :-   6 hours,
    Ref :-   Book : Martindale    Page : 1578   Edition : 38,