Travoprost is a Medicine belongs to Miotics Mydriatics and Antiglaucoma drug group whose information about Brand can be referenced from   Book : Martindale    Page : 2048   Edition : 37  

  ►   Brandname : travatan
  ►  Strength : Ophthalmic Solution with 0.004 %. 

Reference of this Medicine for its Strength can be taken from   Book : Martindale    Page : 2048   Edition : 37  
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : ophthalmic
Reference :-   Book : Martindale    Page : 2048   Edition : 37  

Dosing of Medicine differ in Adult & Pediatrics ↓

Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Open-angle glaucoma and ocular hypertension ophthalmic 0.004 % Ophthalmic Solution o.d.

Ref :-  Book : Martindale    Page : 2048   Edition : 37  



Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1

Ref :- Book :    Page :    Edition :   
►  Side Effect : Increase in the amount of brown pigment in the iris, Change in eye colour, Darkening, thickening, and lengthening of eye lashes, Ocular irritation, Conjunctival hyperaemia, Transient punctate epithelial erosions , Eyelid oedema, Dizziness, Headache, Arthralgia, Myalgia
Ref :-   Book : Martindale    Page : 2044, 2048   Edition : 37.  

►  Drug Interaction : Drug interaction of Travoprost is with NA

  ►    Mechanism of Drug Drug Interaction :  N.F.R.B
Ref :-   Book :    Page :    Edition : .  


►  Contraindication : N.F.R.B.
Ref :-   Book :    Page :    Edition : .  
  ►  Mechanism of Action :   Travoprost, bind to FP receptors that link to Gq11 and then to the PLC–IP3–Ca2+ pathway. This pathway is active in isolated human ciliary muscle cells. Other cells in the eye also may express FP receptors. Theories of IOP lowering by PGF2 range from altered ciliary muscle tension to effects on trabecular meshwork cells to release of matrix metalloproteinases and digestion of extracellular matrix materials that may impede outflow tracts.
Ref :-   Book : Goodman    Page : 1787   Edition : 12.  

Pathway of DIETARY Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


DIETARY Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication DIETARY Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   NA

►    Plasma Half-life :   Min value :-   NA    Max value :-   NA

►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA