Trientine dihydrochloride(TETA) is a Medicine belongs to Chelators Antidotes and Antagonists group whose information about Brand can be referenced from   Book : Martindale    Page : 1610   Edition : 37,

  ►   Brandname : Syprine

  ►  Strength : Capsule with NF  ,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page :    Edition : ,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Martindale    Page : 1610   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Wilson’s disease Oral 0.75 1.25 gm Capsule Dose: Given on an empety stomach daily in 2 to 4 divided doses.

Ref :-  Book : Davidson's Principles and Practice of Medicine    Page : 1610   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Wilson’s disease Oral 500 750 mg Capsule

Ref :- Book : Martindale    Page : 1610   Edition : 37,
►  Side Effect : nausea, Skin rashes, duodenitis, colitis,
Ref :-   Book : Martindale    Page : 1610   Edition : 37,

►  Drug Interaction : Drug interaction of Trientine dihydrochloride(TETA) is with Lacosamide , ,
Ref :-   Book : Martindale    Page : 1610.1   Edition : 37,


  ►    Mechanism of Drug Drug Interaction :  Chelation of trientine with metal ions in the diet reduces the absorption ,
Ref :-   Book : Martindale    Page : 1610   Edition : 37,


►  Contraindication : ,
Ref :-   Book :    Page :    Edition : ,
  ►  Mechanism of Action :   It chelates copper ions,
Ref :-   Book : Martindale    Page : 1610   Edition : 37,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Sage with Another pathway,

  ►  Pathway with its reference as follows :-
  • copper chelator --- ( Stef, D. & Gergen, I. (2012). Effect of mineral-enriched diet and medicinal herbs on Fe, Mn, Zn, and Cu uptake in chicken. Chemistry Central Journal, 6(1), 19. )

  •   ►  URL -- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337232/,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   NA


    ►    Plasma Half-life :
      Min value :-   NA    Max value :-   NA


    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA