Trientine dihydrochloride(TETA) is a Medicine belongs to Chelators Antidotes and Antagonists group whose information about Brand can be referenced from   Book : Martindale    Page : 1610   Edition : 37  

  ►   Brandname : Syprine
  ►  Strength : Capsule with

Reference of this Medicine for its Strength can be taken from   Book : Martindale    Page : 1610   Edition : 37  
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral
Reference :-   Book : Martindale    Page : 1610   Edition : 37  

Dosing of Medicine differ in Adult & Pediatrics ↓

Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Wilson’s disease Oral 0.75 1.25 gm Capsule Dose: Given on an empty stomach daily in 2 to 4 divided doses; this may be increased to a maximum of 2 g daily if required.

Ref :-  Book : Martindale    Page : 1610   Edition : 37  



Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Wilson’s disease Oral 500 750 mg Capsule

Ref :- Book : Martindale    Page : 1610   Edition : 37  
►  Side Effect : Nausea, Skin rashes, Duodenitis, Colitis
Ref :-   Book : Martindale    Page : 1610   Edition : 37.  

►  Drug Interaction : Drug interaction of Trientine dihydrochloride(TETA) is with NA

  ►    Mechanism of Drug Drug Interaction :  Chelation of trientine with metal ions in the diet reduces the absorption Chelation of trientine with metal ions in the diet or in mineral supplements may impair the absorption of both. Trientine should not be taken with mineral supplements and should be taken at least 1 hour apart from food, other drugs, or milk, to reduce the likelihood of absorption being affected. Iron supplements should be taken at least 2 hours before or after trientine.
Ref :-   Book : Martindale    Page : 1610   Edition : 37.  


►  Contraindication :
Ref :-   Book :    Page :    Edition : .  
  ►  Mechanism of Action :   It chelates copper ions
Ref :-   Book : Martindale    Page : 1610   Edition : 37.  

Pathway of DIETARY Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Sage with Another pathway.  

  ►  Pathway with its reference as follows :-
  • copper chelator --- ( Stef, D. & Gergen, I. (2012). Effect of mineral-enriched diet and medicinal herbs on Fe, Mn, Zn, and Cu uptake in chicken. Chemistry Central Journal, 6(1), 19. )

  •   ►  URL --
  • http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337232/ .

  • DIETARY Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication DIETARY Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   NA

    ►    Plasma Half-life :   Min value :-   NA    Max value :-   NA

    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA