Trifluoperazine is a Medicine belongs to Antipsychotic group whose information about Brand can be referenced from   Book : Martindale    Page : 1141-1142   Edition : 37,

  ►   Brandname : Trinicalm,Stelazine

  ►  Strength : Tablet with 1  mg, Tablet with 2  mg, Tablet with 5  mg, Tablet with 10  mg,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 519   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, IM,
Reference :-   Book : Martindale    Page : 1141   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Nausea Oral 1 2 mg b.d.
2 Vomiting Oral 1 2 mg b.d.
3 Severe anxiety Oral 1 2 mg b.d.
4 Psychoses Oral 2 5 mg b.d.

Ref :-  Book : Martindale    Page : 1141   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Psychoses >12 Year Oral up to 5 mg
2 Psychoses 6 Year 12 Year Oral 15 mg
3 Nausea 3 Year 5 Year 1 mg
4 Vomiting 3 Year 5 Year 1 mg
5 Severe anxiety 3 Year 5 Year 1 mg
6 Nausea 6 Year 12 Year 4 mg
7 Vomiting 6 Year 12 Year 4 mg
8 Severe anxiety 6 Year 12 Year 4 mg

Ref :- Book : Martindale    Page : 1141   Edition : 37,
►  Side Effect : dry mouth, constipation, difficulty in micturition, Blurred Vision, mydriasis, delirium, agitation, exfoliative dermatitis, erythema multiforme, contact sensitivity, photosensitivity, haemolytic anaemia, aplastic anaemia, thrombocytopenic purpura, eosinophilia,
Ref :-   Book : Martindale    Page : 1072, 1141   Edition : 37,

►  Drug Interaction : Drug interaction of Trifluoperazine is with Zonisamide , Testosterone , Norgestrel , Bezafibrate , Ethinylestradiol , Guanethidine, Metrizamide, Amiodarone , Disopyramide , Procainamide , Quinidine , Rifampicin , Isoniazid , Carbamazapine , Phenobarbital , Diazoxide , Phenytoin ,
Ref :-   Book : Martindale    Page : 1076   Edition : 37,


  ►    Mechanism of Drug Drug Interaction :  NA


►  Contraindication : Myelosuppression, , Parkinson’s disease,
Ref :-   Book : Martindale    Page : 1141   Edition : 37,
  ►  Mechanism of Action :   NA

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- AGNUS CASTUS I.E. NIRGANDHI with Nirgandhi interact with dopamine antagosit drug,

  ►  Reference :-
  • Driver, S. (2009). Stockleys Herbal Medicines Interactions. Royal pharmaceutical Society of Great Britain: Pharmaceutical press.

  •   ►  URL -- https://www.stonybrookmedicine.edu/sites/default/files/herbal_medicines_interactions-1.pdf,

    ►   Route of Elimination :   NA


    ►    Plasma Half-life :   Min value :-   22 hours,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 1141   Edition : 37,


    ►    Peak Plasma Concentration :   Min value :-   1.5 hours,    Max value :-   6 hours,
    Ref :-   Book : Martindale    Page : 1141   Edition : 37,