Trifluridine is a Medicine belongs to Antiviral group whose information about Brand can be referenced from   Book : Martindale    Page : 1020   Edition : 38,

  ►   Brandname : Viroptic

  ►  Strength : Ophthalmic Solution with 1  %,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 889   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Topical,
Reference :-   Book : Martindale    Page : 1020   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Keratoconjunctivitis ophthalmic 1 % Solution Dose: Instilled into the eye(s) every 2 hours.
2 Recurrent epithelial keratitis ophthalmic 1 % Solution Dose: Instilled into the eye(s) every 2 hours.

Ref :-  Book : Martindale    Page : 1020   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : palpebral edema, hypersensitivity reactions, Irritation, superficial punctate keratitis, epithelial keratopathy,
Ref :-   Book : Martindale    Page : 1020   Edition : 38,

►  Drug Interaction : Drug interaction of Trifluridine is with NA

  ►    Mechanism of Drug Drug Interaction :  NF,
Ref :-   Book :    Page :    Edition : ,


►  Contraindication : ,
Ref :-   Book :    Page :    Edition : ,
  ►  Mechanism of Action :   Trifluridine (trifluorothymidine) is a fluorinated pyrimidine nucleoside that inhibits viral DNA synthesis in HSV-1, HSV-2, CMV, vaccinia, and some adenoviruses,
Ref :-   Book : Basic & Clinical pharmacology    Page : 866   Edition : 12,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Garlic with Another pathway, Alpine cranberry with Another pathway,

  ►  Pathway with its reference as follows :-
  • Anti-viral effect --- (Antiviral Properties of Garlic Cloves Juice Compared with Onion Bulbs Juice Against Potato Virus Y (PVY). (2016). Journal Of American Science, 6(8). )
  • Acylphloroglucinols have Anti-viral effect --- (AB, H. (2010). Antiviral effects of cranberry juice and cranberry proanthocyanidins on foodborne viral surrogates--a time dependence study in vitro. Food Microbiol., 27(8). http://dx.doi.org/10.1016/j.fm.2010.05.027 )

  •   ►  URL -- http://www.jofamericanscience.org/journals/am-sci/am0608/39_2830_am0608_302_310.pdf, http://www.ncbi.nlm.nih.gov/pubmed/20832675,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   NA


    ►    Plasma Half-life :
      Min value :-   NA    Max value :-   NA


    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA