Tubocurarine Chloride is a Medicine belongs to Neuromuscular blocker group whose information about Brand can be referenced from   Book : Martindale    Page : 2076   Edition : 37,

  ►   Brandname : Curarine,Tubarine

  ►  Strength : Injection with 3  mg/ml,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 481   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : IV,
Reference :-   Book : Basic & Clinical pharmacology    Page : 481   Edition : 12,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info

Ref :-  Book :




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : transient fall in blood pressure, increases in heart rate,
Ref :-   Book : Martindale    Page : 2076   Edition : 37,

►  Drug Interaction : Drug interaction of Tubocurarine Chloride is with NA

  ►    Mechanism of Drug Drug Interaction :  Inhaled (volatile) anesthetics potentiate the neuromuscular blockade produced by nondepolarizing muscle relaxants in a dose-dependent fashion. 1. Nervous system depression at sites proximal to the neuromuscular junction i.e., central nervous system 2. Increased muscle blood flow i.e., due to peripheral vasodilation produced by volatile anesthetics, which allows a vasodilation produced by volatile anesthetics. 3. Decreased sensitivity of the postjunctional membrane to depolarization....enhancement of neuromuscular blockade by antibiotics eg, aminoglycosides.... effect of succinylcholine can be antagonized by adminsitering a small dose of a nondepolarizing blocker,
Ref :-   Book : Basic & Clinical pharmacology    Page : 475   Edition : 12,


►  Contraindication : renal impairment,
Ref :-   Book : Martindale    Page : 2076   Edition : 37,
  ►  Mechanism of Action :   competitive antagonist at nAch recptors, especially at neuromuscular junctions,
Ref :-   Book : Basic & Clinical pharmacology    Page : 475   Edition : 12,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Renal,
Ref :-   Book : Basic & Clinical pharmacology    Page : 40   Edition : 12,


►    Plasma Half-life :
  Min value :-   2 hours,    Max value :-   NA
Ref :-   Book : Basic & Clinical pharmacology    Page : 40   Edition : 12,

►    Peak Plasma Concentration :   Min value :-   nf,    Max value :-   NA
Ref :-   Book :    Page :    Edition : ,