Urea is a Medicine belongs to Dermatological drug group whose information about Brand can be referenced from   Book : Martindale    Page : 1763   Edition : 37,

  ►   Brandname : Aquadrate,Aquacare:BP,Carmol,Gormel,Hydro Kerafoam,Keralac,Kerol,Lanaphilic,Nutraplus,RE-U40,Ultra Mide

  ►  Strength : Cream with 2-20  %, Lotion with   %,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 1075   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Topical, IV,
Reference :-   Book : Martindale    Page : 1727   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Raised intra-ocular pressure IV 0.5 1.5 gm/kg Injection

Ref :-  Book : Martindale    Page : 1727   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Raised intra-ocular pressure >2 Year IV 100 mg/kg Injection

Ref :- Book : Martindale    Page : 1727   Edition : 38,
►  Side Effect : diarrhea, nausea, vomiting, thirst, headache, Dizziness, chills, fever, tachycardia, chest pain, hyponatraemia, dehydration, Blurred Vision, Urticaria, hypotension, hypertension, venous thrombosis, sloughing or necrosis, haemolysis, irritant to sensitive skin, phlebitis at the site of injection,
Ref :-   Book : Martindale    Page : 1728,1428   Edition : 38,

►  Drug Interaction : Drug interaction of Urea is with NA

  ►    Mechanism of Drug Drug Interaction :  nf,
Ref :-   Book :    Page :    Edition : ,


►  Contraindication : hepatic impairment,
Ref :-   Book : Martindale    Page : 1728   Edition : 37,
  ►  Mechanism of Action :   The mechanism of action appears to involve alterations in prekeratin and keratin, leading to increased solubilization. In addition, urea may break hydrogen bonds that keep the stratum corneum intact.,
Ref :-   Book : Basic & Clinical pharmacology    Page : 1075   Edition : 12,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Renal,
Ref :-   Book : Martindale    Page : 1763   Edition : 37,


►    Plasma Half-life :
  Min value :-   12 hours,    Max value :-   NA
Ref :-   Book : Martindale    Page : 799   Edition : 37,

►    Peak Plasma Concentration :   Min value :-   2 hours,    Max value :-   NA
Ref :-   Book :    Page : 799   Edition : 37,