Vildagliptin is a Medicine belongs to Dipeptidylpeptidase-4 inhibitor/antidiabetic group whose information about Brand can be referenced from   Book : Martindale    Page : 506   Edition : 37,    Page :   Edition : ,

  ►   Brandname : Jalra,Galvas,jalra m

  ►  Strength : Tablet with nf  ,

Reference of this Medicine for its Strength can be taken from   Book :    Page :    Edition : ,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, IV,
Reference :-   Book : Martindale    Page : 506   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Type 2 diabetes mellitus Oral 50 mg Tablet b.d.

Ref :-  Book : Martindale    Page : 504   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : Dizziness, headache, peripheral oedema, constipation, upper respiratory-tract infections, arthralgia, hepatitis, nasopharyngitis,
Ref :-   Book : Martindale    Page : 501, 506   Edition : 37,

►  Drug Interaction : Drug interaction of Vildagliptin is with NA

  ►    Mechanism of Drug Drug Interaction :  Efficacy of vildagliptin may be affected by drugs independently increasing or decreasing blood-glucose concentration.,
Ref :-   Book : Martindale    Page : 506   Edition : 37,


►  Contraindication : hepatic impairment, renal impairment,
Ref :-   Book : Martindale    Page : 506   Edition : 37,
  ►  Mechanism of Action :   DPP-4 inhibitor: Blocks degradation of GLP-1, raises circulating GLP-1 levels.,
Ref :-   Book : Basic & Clinical pharmacology    Page : 765   Edition : 12,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Jamun with same pathway, Brazil nuts with Another pathway, Fenugreek seed with Another pathway, Greek Oregano with same pathway, Marjoram with same pathway, Rosemary with same pathway, Maxican oregano with same pathway, Blue Berries with same pathway,

  ►  Pathway with its reference as follows :-
  • DDP inhibitor --- ( Fan, J., Johnson, M., Lila, M., Yousef, G., & de Mejia, E. (2013). Berry and Citrus Phenolic Compounds Inhibit Dipeptidyl Peptidase IV: Implications in Diabetes Management. Evidence-Based Complementary And Alternative Medicine, 2013, 1-13 )
  • Selenium have Antidiabetic Effect --- (Wei, J., Zeng, C., Gong, Q., Yang, H., Li, X., Lei, G., & Yang, T. (2015). The association between dietary selenium intake and diabetes: a cross-sectional study among middle-aged and older adults. Nutrition Journal, 14(1), 18. )
  • Allicin have Antidiabetic Effect --- (PDR for Herbal medicines. (2000) (4th ed.). U.S. )
  • Green oregano act as DDP 4 inhibitor . --- (AM, B. (2014). Bioactive compounds from culinary herbs inhibit a molecular target for type 2 diabetes management, dipeptidyl peptidase IV. PMID: 24881464, 62(26). http://dx.doi.org/10.1021/jf500639f )
  • Marjoram act as ddp 4 inhibitor. --- (AM, B. (2014). Bioactive compounds from culinary herbs inhibit a molecular target for type 2 diabetes management, dipeptidyl peptidase IV. PMID: 24881464, 62(26). http://dx.doi.org/10.1021/jf500639f )
  • Rosemary act as DDP 4 inhibitor. --- (AM, B. (2014). Bioactive compounds from culinary herbs inhibit a molecular target for type 2 diabetes management, dipeptidyl peptidase IV. PMID: 24881464, 62(26). http://dx.doi.org/10.1021/jf500639f )
  • Maxican oregano act as DDP 4 inhibitor. --- ( AM, B. (2014). Bioactive compounds from culinary herbs inhibit a molecular target for type 2 diabetes management, dipeptidyl peptidase IV. PMID: 24881464, 62(26). http://dx.doi.org/10.1021/jf500639f )
  • Blue berrries act as ddp 4 inhibitor . --- (AM, B. (2014). Bioactive compounds from culinary herbs inhibit a molecular target for type 2 diabetes management, dipeptidyl peptidase IV. PMID: 24881464, 62(26). http://dx.doi.org/10.1021/jf500639f )

  •   ►  URL -- http://www.hindawi.com/journals/ecam/2013/479505/, https://nutritionj.biomedcentral.com/articles/10.1186/s12937-015-0007-2, http://www.travolekar.ru/arch/Pdr_for_Herbal_Medicines.pdf, https://www.ncbi.nlm.nih.gov/pubmed/24881464,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Fecal, Renal,
    Ref :-   Book : Martindale    Page : 506   Edition : 37,


    ►    Plasma Half-life :
      Min value :-   2 hours,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 506   Edition : 37,

    ►    Peak Plasma Concentration :   Min value :-   1.7 hours,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 506   Edition : 37,