Vitamin B1 (Thiamine/Benfotiamine) is a Medicine belongs to Vitamin group whose information about Brand can be referenced from   Book : Martindale    Page : 2104   Edition : 38,    Page :   Edition : ,

  ►   Brandname : Arcalion,Benalgis,Benfage,Berin,Benerva,Tyvera,A to Z,A TO Z GOLD,Becosule ,health ok,Nurokind Gold,Wellwoman tablet,Meganeuron Plus,Polybion,Zincovit

  ►  Strength : Tablet with 50  mg, Tablet with 100  mg, Tablet with 250  mg, Tablet with 500  mg, Capsule with 50  mg, Capsule with 100  mg, Capsule with 250  mg, Capsule with 500  mg, Injection with 100  mg/ml,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 400   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, IM, IV,
Reference :-   Book : Martindale    Page : 2103   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Mild chronic thiamine deficiency Oral 10 50 mg Daily, in single or divided dose. Other compounds that possess vitamin B1 activity and may be given as alternatives to thiamine include Benfotiamine, cycotiamine, octotiamine etc.
2 Severe thiamine deficiency Oral up to 300 mg Given Daily. Other compounds that possess vitamin B1 activity and may be given as alternatives to thiamine include Benfotiamine, cycotiamine, octotiamine etc.

Ref :-  Book : Martindale    Page : 2103   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Vitamin B deficiency 1 Month 1 Year Oral 5 mg t.i.d.
2 Vitamin B deficiency 1 Year 12 Year Oral 10 mg t.i.d.
3 Vitamin B deficiency 12 Year 18 Year Oral 10 15 mg t.i.d.
4 Maple syrup urine disease Oral 5 mg/kg
5 Congenital lactic acidosis 1Month IV 50 200 mg Injection
6 Congenital lactic acidosis 1 Month 18 Year IV 100 300 mg Injection

Ref :- Book : Martindale    Page : 2103   Edition : 38,
►  Side Effect : hypersensitivity reactions, ,
Ref :-   Book : Martindale    Page : 2103   Edition : 38,

►  Drug Interaction : Drug interaction of Vitamin B1 (Thiamine/Benfotiamine) is with NA

  ►    Mechanism of Drug Drug Interaction :  ,
Ref :-   Book :    Page :    Edition : ,


►  Contraindication : , Hypersensitivity,
Ref :-   Book :    Page :    Edition : , Martindale    Page : 2103   Edition : 38,
  ►  Mechanism of Action :   Thiamine is a water-soluble vitamin, although some of its derivatives have greater lipophilicity. It is an essential coenzyme for carbohydrate metabolism in the form of the diphosphate (thiamine pyrophosphate, cocarboxylase),
Ref :-   Book : Martindale    Page : 2103   Edition : 38,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Wheat germ oil with same compound, Wheat germ with same compound,

  ►  Pathway with its reference as follows :-
  • Nutritional Supplement --- (Gopalan, C. (2012). Nutritive value of Indian foods. National Institute of Nutrition ,ICMR.: Hyderabad 500007,INDIA. )
  • Nutritional supplement --- (Swaminathan, M. (2016). Advanced Text-Book On Food & Nutrition vol 2. Bangalore: Wesley press,Mysore and Diocesan press Madras. )

  •   ►  URL -- https://books.google.co.in/books/about/Nutritive_Value_of_Indian_Foods.html?id=biFBAAAAYAAJ, https://www.sapnaonline.com/books/advanced-text-book-on-food-nutrition-vol-2-3473,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Renal,
    Ref :-   Book : Martindale    Page : 2103   Edition : 38,


    ►    Plasma Half-life :
      Min value :-   NA    Max value :-   NA


    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA