Vitamin B1 (Thiamine/Benfotiamine) is a Medicine belongs to Vitamin group whose information about Brand can be referenced from   Book : Martindale    Page : 2104   Edition : 38      Page :   Edition :   

  ►   Brandname : Arcalion, Benalgis, Benfage, Berin, Benerva, Tyvera, A to Z, A TO Z GOLD, Becosule , health ok, Nurokind Gold, Wellwoman tablet, Meganeuron Plus, Zincovit
  ►  Strength : Tablet with 50 mg.  Tablet with 100 mg.  Tablet with 250 mg.  Tablet with 500 mg.  Capsule with 50 mg.  Capsule with 100 mg.  Capsule with 250 mg.  Capsule with 500 mg.  Injection with 100 mg/ml.  Oral solution with .  Elixir with

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 400   Edition : 12   Martindale    Page : 2104   Edition : 38  
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, IM, IV infusion
Reference :-   Book : Martindale    Page : 2103   Edition : 38  

Dosing of Medicine differ in Adult & Pediatrics ↓

Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Mild chronic thiamine deficiency Oral 10 50 mg Daily, in single or divided dose.
2 Severe thiamine deficiency Oral up to 300 mg Given Daily.

Ref :-  Book : Martindale    Page : 2103   Edition : 38  



Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Vitamin B deficiency 1 Month 1 Year Oral 5 mg t.i.d.
2 Vitamin B deficiency 1 Year 12 Year Oral 10 mg t.i.d.
3 Vitamin B deficiency 12 Year 18 Year Oral 10 15 mg t.i.d.
4 Maple syrup urine disease Oral 5 mg/kg
5 Congenital lactic acidosis Up to 1Month Oral / i.v 50 200 mg Injection
6 Congenital lactic acidosis 1 Month 18 Year Oral / i.v 100 300 mg Injection

Ref :- Book : Martindale    Page : 2103   Edition : 38  
►  Side Effect : Hypersensitivity reactions
Ref :-   Book : Martindale    Page : 2103   Edition : 38.  

►  Drug Interaction : Drug interaction of Vitamin B1 (Thiamine/Benfotiamine) is with NA

  ►    Mechanism of Drug Drug Interaction :  N.F.R.B
Ref :-   Book :    Page :    Edition : .  


►  Contraindication :
Ref :-   Book :    Page :    Edition : .  
  ►  Mechanism of Action :   Thiamine is a water-soluble vitamin, although some of its derivatives have greater lipophilicity. It is an essential coenzyme for carbohydrate metabolism in the form of the diphosphate (thiamine pyrophosphate, cocarboxylase)
Ref :-   Book : Martindale    Page : 2103   Edition : 38.  

Pathway of DIETARY Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Wheat germ oil with same compound.   Wheat germ with same compound.  

  ►  Pathway with its reference as follows :-
  • Nutritional Supplement --- (Gopalan, C. (2012). Nutritive value of Indian foods. National Institute of Nutrition ,ICMR.: Hyderabad 500007,INDIA. )
  • Nutritional supplement --- (Swaminathan, M. (2016). Advanced Text-Book On Food & Nutrition vol 2. Bangalore: Wesley press,Mysore and Diocesan press Madras. )

  •   ►  URL --
  • https://books.google.co.in/books/about/Nutritive_Value_of_Indian_Foods.html?id=biFBAAAAYAAJ .
  • https://www.sapnaonline.com/books/advanced-text-book-on-food-nutrition-vol-2-3473 .

  • DIETARY Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication DIETARY Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Renal
    Ref :-   Book : Martindale    Page : 2103   Edition : 38.  

    ►    Plasma Half-life :   Min value :-   NA    Max value :-   NA

    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA