Vitamin K is a Medicine belongs to Vitamin group whose information about Brand can be referenced from   Book : Martindale    Page : 2125   Edition : 38,    Page :   Edition : ,

  ►   Brandname : Injek,K-Nat,Kenadione,Konakion,Neokay,Mephyton,A to Z

  ►  Strength : Tablet with 5  mg, Injection with 2  mg/ml, Injection with 10  mg/ml,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 617   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, IM, SC, IV,
Reference :-   Book : Martindale    Page : 2122   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Haemorrhage IV 0.5 10 mg Injection

Ref :-  Book : Martindale    Page : 2122   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Vitamin K deficiency Oral 1 mg Tablet o.d.
2 Haemorrhage 1 Month 18 Year IV 15 30 micrograms/kg Injection
3 Vitamin K deficiency 1 Year 12 Year Oral 5 10 mg Tablet
4 Vitamin K deficiency 12 Year 18 Year Oral 10 20 mg Tablet

Ref :- Book : Nelson's textbook of Pediatrics    Page : 211   Edition : 19, Martindale    Page : 2122   Edition : 38,
Precaution :- If a Patient is using 'Vitamin K' drug in  ObstetricCholestasis  disease, then Please Contraindication: G-6 PD deficiency Vitamin K allergy .

►  Side Effect : facial flushing, sweating, chest pain, dyspnoea, cyanosis, cardiovascular collapse, fatalities, Pain, swelling, phlebitis, atrophy, necrosis,
Ref :-   Book : Martindale    Page : 2124   Edition : 38,

►  Drug Interaction : Drug interaction of Vitamin K is with Ropinirole ,
Ref :-   Book : Martindale    Page : 2125   Edition : 37,


  ►    Mechanism of Drug Drug Interaction :  Vitamin K decreases the effects of oral anticoagulants.,
Ref :-   Book : Martindale    Page : 2125   Edition : 38,


►  Contraindication : hepatic impairment, kernicterus, hyperbilirubinaemia, premature infants, haemolytic anaemia,
Ref :-   Book : Martindale    Page : 2124   Edition : 38,
  ►  Mechanism of Action :   Vitamin K is an essential cofactor in the hepatic synthesis of prothrombin and other blood clotting factors (factors VII, IX, and X, and proteins C and S) and in the function of proteins such as osteocalcin important for bone development,
Ref :-   Book : Martindale    Page : 2122   Edition : 38,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- with same compound,

  ►  Pathway with its reference as follows :-
  • Nutritional Supplement --- (Gopalan, C. (2012). Nutritive value of Indian foods. National Institute of Nutrition ,ICMR.: Hyderabad 500007,INDIA. )

  •   ►  URL -- https://books.google.co.in/books/about/Nutritive_Value_of_Indian_Foods.html?id=biFBAAAAYAAJ,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Biliary, Renal,
    Ref :-   Book : Martindale    Page : 2125   Edition : 38,


    ►    Plasma Half-life :
      Min value :-   NA    Max value :-   NA


    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA