Vitamin K is a Medicine belongs to Vitamin group whose information about Brand can be referenced from   Book : Martindale    Page : 2125   Edition : 38      Page :   Edition :   

  ►   Brandname : Injek, K-Nat, Kenadione, Konakion, Neokay, Mephyton, A to Z
  ►  Strength : Tablet with 5 mg.  Injection with 2 mg/ml.  Injection with 10 mg/ml. 

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 617   Edition : 12  
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, IM, SC, IV
Reference :-   Book : Martindale    Page : 2122   Edition : 38  

Dosing of Medicine differ in Adult & Pediatrics ↓

Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Haemorrhage IV 0.5 10 mg Injection

Ref :-  Book : Martindale    Page : 2122   Edition : 38  



Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Vitamin K deficiency Oral 1 mg Tablet o.d.
2 Haemorrhage 1 Month 18 Year IV 15 30 micrograms/kg Injection
3 Vitamin K deficiency 1 Year 12 Year Oral 5 10 mg Tablet
4 Vitamin K deficiency 12 Year 18 Year Oral 10 20 mg Tablet

Ref :- Book : Nelson's textbook of Pediatrics    Page : 211   Edition : 19   Martindale    Page : 2122   Edition : 38  
Precaution :- If a Patient is using 'Vitamin K' drug in  ObstetricCholestasis  disease, then Please Contraindication: G-6 PD deficiency Vitamin K allergy .

►  Side Effect : Facial flushing, Sweating, Chest pain, Dyspnoea, Cyanosis, Cardiovascular collapse, Fatalities, Pain, Swelling, Phlebitis, Atrophy, Necrosis
Ref :-   Book : Martindale    Page : 2124   Edition : 38.  

►  Drug Interaction : Drug interaction of Vitamin K is with Ropinirole
Ref :-   Book : Martindale    Page : 2125   Edition : 37.  


  ►    Mechanism of Drug Drug Interaction :  Vitamin K decreases the effects of oral anticoagulants.
Ref :-   Book : Martindale    Page : 2125   Edition : 38.  


►  Contraindication : Hepatic impairment, Kernicterus, Hyperbilirubinaemia, Premature infants, Haemolytic anaemia
Ref :-   Book : Martindale    Page : 2124   Edition : 38.  
  ►  Mechanism of Action :   Vitamin K is an essential cofactor in the hepatic synthesis of prothrombin and other blood clotting factors (factors VII, IX, and X, and proteins C and S) and in the function of proteins such as osteocalcin important for bone development
Ref :-   Book : Martindale    Page : 2122   Edition : 38.  

Pathway of DIETARY Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


DIETARY Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication DIETARY Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Biliary, Renal
Ref :-   Book : Martindale    Page : 2125   Edition : 38.  

►    Plasma Half-life :   Min value :-   NA    Max value :-   NA

►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA