Voglibose is a Medicine belongs to Antidiabetic group whose information about Brand can be referenced from   Book :    Page :   Edition :   

  ►   Brandname : Voglistar MD, Voglistar
  ►  Strength : Tablet with 0.2 mg.  Tablet with 0.3 mg. 

Reference of this Medicine for its Strength can be taken from   Book : Martindale    Page : 506   Edition : 37  
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral
Reference :-   Book : Martindale    Page : 506   Edition : 37  

Dosing of Medicine differ in Adult & Pediatrics ↓

Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Diabetes mellitus Oral 200 300 micrograms Tablet t.i.d. Dose: Given immediately before meals.

Ref :-  Book : Martindale    Page : 506   Edition : 37  

Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :    Page :    Edition :   
►  Side Effect : Gastrointestinal disturbances, Flatulence, Abdominal distension, Diarrhoea, Pain, Transient and reversible increase in liver enzyme values
Ref :-   Book : Martindale    Page : 471,506   Edition : 37.  

►  Drug Interaction : Drug interaction of Voglibose is with Insulin , Neomycin , Cholestyramine , Digoxin
Ref :-   Book : Martindale    Page : 471   Edition : 37.  

  ►    Mechanism of Drug Drug Interaction :  Voglibose may enhance the effects of other antidiabetics, including insulin, and a reduction in their dosage may be needed. Use with gastrointestinal adsorbents and digestive enzyme preparations can diminish the effects of voglibose and should be avoided. Neomycin and colestyramine may enhance the effects of acarbose and a reduction in its dosage may be required. Voglibose may inhibit the absorption of digoxin.
Ref :-   Book : Martindale    Page : 471,506   Edition : 37.  

►  Contraindication : Voglibose is contra-indicated in inflammatory bowel disease, particularly where there is associated ulceration, and in gastrointestinal obstruction or patients predisposed to it. It should be avoided in patients with chronic intestinal diseases that significantly affect digestion or absorption, and in conditions which may deteriorate as a result of increased gas formation, such as hernia, Voglibose is also contra-indicated in patients with hepatic impairment and liver enzyme values should be monitored, particularly during the first 6 to 12 months of therapy and at high dose , Voglibose given alone should not cause hypoglycaemia, but may potentiate the effects of sulfonylureas and insulin. If hypoglycaemia should develop in a patient receiving acarbose it needs to be treated with glucose, since the action of acarbose inhibits the hydrolysis of disaccharides.
Ref :-   Book : Martindale    Page : 471,506   Edition : 37.  
  ►  Mechanism of Action :   Voglibose is an inhibitor of alpha glucosidases, especially sucrase. This slows the digestion and absorption of carbohydrates in the small intestine and hence reduces the increase in blood-glucose concentrations after a carbohydrate load.
Ref :-   Book : Martindale    Page : 471, 506   Edition : 37.  

Pathway of DIETARY Product

​   ► Act.Comp / Nutrient / Food / Herb as follows :- Arjun Bark with same pathway.   Ceylon leadwort with same pathway.  

  ►  Pathway with its reference as follows :-
  • Arjun Bark act as alpha-glucosidase inhibitor . --- ( J, A., & SHIHABUDEEN, M. (2011). SCREENING OF FIFTEEN INDIAN AYURVEDIC PLANTS FOR ALPHA-GLUCOSIDASE INHIBITORY ACTIVITY AND ENZYME KINETICS. International Journal Of Pharmacy And Pharmaceutical Sciences, 3(4), 267-274. )

  •   ►  URL --
  • http://www.ijppsjournal.com/Vol3Suppl4/2436.pdf .

  • DIETARY Substance Interactions

    ​   ► This Medicine interact with :- NA

    ContraIndication DIETARY Substance

    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   NA

    ►    Plasma Half-life :   Min value :-   NA    Max value :-   NA

    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA