Zanamivir is a Medicine belongs to Antiviral group whose information about Brand can be referenced from   Book : Martindale    Page : 1024   Edition : 38,

  ►   Brandname : Relenza

  ►  Strength : Inhalant with 4  mg,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 889   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : inhalation,
Reference :-   Book : Basic & Clinical pharmacology    Page : 889   Edition : 12,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Prophylaxis of influenza A and B inhalation 10 mg Aerosol b.d.
2 Seasonal prophylaxis inhalation 10 mg Aerosol o.d.

Ref :-  Book : Martindale    Page : 1024   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : headache, nasal symptoms, bronchitis, Cough, gastrointestinal effects, abnormal behaviour, Acute bronchospasm or decline in respiratory function, delirium, oropharyngeal oedema, severe skin rashes,
Ref :-   Book : Martindale    Page : 1009   Edition : 37,

►  Drug Interaction : Drug interaction of Zanamivir is with NA

  ►    Mechanism of Drug Drug Interaction :  nf,
Ref :-   Book :    Page :    Edition : ,


►  Contraindication : Bronchospasm, nebuliser or mechanical ventilator,
Ref :-   Book : Martindale    Page : 1028   Edition : 38, Martindale    Page : 1024   Edition : 38,
  ►  Mechanism of Action :   Zanamivir inhibits the viral surface enzyme neuraminidase (sialidase) which is essential for the release of newly formed viral particles from infected cells, and may facilitate access of virus through mucus to the cell surface,
Ref :-   Book : Martindale    Page : 1024   Edition : 38,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Guava with same compound, Tulsi with Another pathway, Chammomila with Another pathway, Quercetin with Another pathway, Parsley with Another pathway, Rosemary with Another pathway, Oregano with Another pathway, Thyme with Another pathway,

  ►  Pathway with its reference as follows :-
  • Rich in Sialic Acid . --- (PDR for Herbal medicines. (2000) (4th ed.). U.S. )
  • eugenol have antiviral property. --- (Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand )
  • Chammomila rich in apigenin enhance the antiviral activity of aciclovir --- (Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand )
  • Quercetin enhance the antiviral activity of aciclovir --- (Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand )
  • Parsley rich in apigenin enhance the antiviral activity of aciclovir. --- (Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand )
  • Rosemary rich in apigenin enhance the antiviral activity of aciclovir . --- (Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand )
  • Oregano rich in apigenin enhance the antiviral activity of aciclovir. --- (Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand )
  • Thyme rich in apigenin enhance the antiviral activity of aciclovir. --- (Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand )

  •   ►  URL -- http://www.travolekar.ru/arch/Pdr_for_Herbal_Medicines.pdf, https://books.google.co.in/books?id=WZhj8EO9N3sC&pg=PA49&lpg=PA49&dq=The+New+Age+of+nutritional+and+herbal+remedies.++book&source=bl&ots=UVld-vNZL0&sig=5KwkKUUvW45p0TkfVUCtMZxnbow&hl=en&sa=X&ved=0ahUKEwiajLCNocrOAhVMto8KHfD2D-4Q6AEIMDAE#v=onepage&q=The%20,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Fecal, Renal,
    Ref :-   Book : Martindale    Page : 1009   Edition : 37,


    ►    Plasma Half-life :
      Min value :-   2.6 hours,    Max value :-   5 hours,
    Ref :-   Book : Martindale    Page : 1009   Edition : 37,

    ►    Peak Plasma Concentration :   Min value :-   1 hours,    Max value :-   2 hours,
    Ref :-   Book : Martindale    Page : 1009   Edition : 37,