Medicine :   
Nefopam is a Medicine belongs to Analgesics/Anti-inflammatory Drugs/Antipyretics group whose properties about Brand can be referenced from   Book : Martindale    Page : 98   Edition : 37,

  ►   Brandname : Acupan

  ►  Doseform : Injection with   ,

Reference of this Medicine for its Strength can be taken from   Book : Martindale    Page : 98   Edition : 37,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, IM, IV,
Reference :-   Book : Martindale    Page : 98   Edition : 37,

  ►  Indication/uses : Relief of moderate acute and chronic pain,
Reference :-   Book : Martindale    Page : 98   Edition : 37,
Dosing of Medicine differ in Adult & Pediatrics ↓


► Nefopam medicine for Adults :

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage   Frequency   Additional Info
1 Relief of moderate acute and chronic pain Oral 30 90 mg Tablet t.i.d. the recommended initial dose is 60 mg (or 30 mg in elderly patients) three times daily
2 Relief of moderate acute and chronic pain slow i.v 20 mg Injection Dose: Given every 4 hours up to a maximum of 120 mg daily
3 Relief of moderate acute and chronic pain IM 20 mg Injection Dose: Repeated every 6 hours if necessary; it has been recommended that the patient should always be lying down when receiving the injection and should remain so for 15 to 20 minutes afterwards.

Ref :-  Book : Martindale    Page : 98   Edition : 37,




For Pediatric :
S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage   Additional Info  

Ref :- Book :
►  Side Effect : nausea, vomiting, sweating, drowsiness, insomnia, urinary retention, Dizziness, hypotension, tremor, paraesthesia, palpitations, lightheadedness, Confusion, Nervousness, Blurred Vision, headache, dry mouth, angioedema, allergic reaction, tachycardia, euphoria, hallucinations, Convulsions, syncope,
Ref :-   Book : Martindale    Page : 98   Edition : 37,

►  Interaction : , ,
Ref :-   Book : Martindale    Page : 98   Edition : 37,


►  Contraindication : History of convulsive disorders, It should be used with caution in the elderly and in patients with glaucoma, urinary retention, or impaired hepatic or renal function,
Ref :-   Book : Martindale    Page : 98   Edition : 37,
  ►    Mechanism of Drug Drug Interaction :  It has been recommended that nefopam should not be given to patients receiving MAOIs and should be used cautiously in those receiving tricyclic antidepressants. The adverse effects of nefopam may be additive to those of other drugs with antimuscarinic or sympathomimetic activity.,
Ref :-   Book : Martindale    Page : 98   Edition : 37,


  ►  Mechanism of Action :   Nefopam hydrochloride is a non-opioid analgesic considered to act centrally, although its mechanism of action is unclear. It also has some antimuscarinic and sympathomimetic actions. ,
Ref :-   Book : Martindale    Page : 98   Edition : 37,
 ►   

Dietary Products that produce same effect as  Nefopam






►   Route of Elimination :   Fecal, Renal,
Ref :-   Book : Martindale    Page : 98   Edition : 37,


►    Plasma Half-life :   Min value :-   4 hours,    Max value :-   NA
Ref :-   Book : Martindale    Page : 98   Edition : 37,


►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA