Medicine :   
Nitazoxanide is a Medicine belongs to Antiprotozoals group whose properties about Brand can be referenced from   Book : Martindale    Page : 930   Edition : 37,

  ►   Brandname : Alinia

  ►  Doseform : Tablet with 500  mg, Oral solution with 100  mg/5mL,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 935   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Martindale    Page : 930   Edition : 37,

  ►  Indication/uses : Cryptosporidiosis and giardiasis,
Reference :-   Book : Martindale    Page : 930   Edition : 37,
Dosing of Medicine differ in Adult & Pediatrics ↓


► Nitazoxanide medicine for Adults :

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage   Frequency   Additional Info
1 Cryptosporidiosis and giardiasis Oral 500 mg Tablet t.i.d. Dose: Given for 3 days

Ref :-  Book : Martindale    Page : 930   Edition : 37,




For Pediatric :
S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage   Additional Info  
1 Cryptosporidiosis and giardiasis 1 Year 3 Year Oral 100 mg Tablet
2 Cryptosporidiosis and giardiasis 4 Year 11 Year Oral 200 mg Tablet

Ref :- Book : Martindale    Page : 930   Edition : 37,
►  Side Effect : abdominal pain, diarrhoea, nausea, vomiting, headache, anorexia, fever, Flatulence, pruritus, Dizziness, Increased creatinine , ,
Ref :-   Book : Martindale    Page : 930   Edition : 37,

►  Interaction : NA

►  Contraindication : ,
Ref :-   Book :    Page :    Edition : ,
  ►    Mechanism of Drug Drug Interaction :  ,
Ref :-   Book :    Page :    Edition : ,


  ►  Mechanism of Action :   Nitazoxanide interferes with the pyruvate:ferredoxin oxidoreductase (PFOR) enzyme-dependent electron-transfer reaction, which is essential to anaerobic metabolism in protozoan and bacterial species.,
Ref :-   Book : Goodman    Page : 1432   Edition : 12,
 ►   

Dietary Products that produce same effect as  Nitazoxanide

  •    Eucalyptus oil ,    Red algae, have compounds that have the same effect as Nitazoxanide through an alternate pathway





►   Route of Elimination :   Renal, Biliary, Faecal,
Ref :-   Book : Martindale    Page : 930   Edition : 37,


►    Plasma Half-life :   Min value :-   NA    Max value :-   NA


►    Peak Plasma Concentration :   Min value :-   1 hours,    Max value :-   4 hours,
Ref :-   Book : Martindale    Page : 930   Edition : 37,