Medicine :   
Nitisinone is a Medicine belongs to Miscellaneous group whose properties about Brand can be referenced from   Book : Martindale    Page : 2584   Edition : 37,

  ►   Brandname : Orfadin

  ►  Doseform :

A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Martindale    Page : 2584   Edition : 37,

  ►  Indication/uses : Hereditary tyrosinaemia type 1,
Reference :-   Book : Martindale    Page : 2585   Edition : 37,
Dosing of Medicine differ in Adult & Pediatrics ↓


► Nitisinone medicine for Adults :

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage   Frequency   Additional Info
1 Hereditary tyrosinaemia type 1 Oral 1 mg/kg Capsule Dose: daily dosage should be given in 2 divided doses, which may be unequally split. If necessary, the daily dose may be increased to 1.5 mg/kg after one month; the maximum daily dose is 2 mg/kg.

Ref :-  Book : Martindale    Page : 2584   Edition : 37,




For Pediatric :
S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage   Additional Info  

Ref :- Book :
►  Side Effect : granulocytopenia, neutropenia, thrombocytopenia, conjunctivitis, corneal opacities, keratitis, photophobia, eye pain,
Ref :-   Book : Martindale    Page : 2584   Edition : 37,

►  Interaction : NA

►  Contraindication : , Breast feeding,
Ref :-   Book :    Page :    Edition : , Martindale    Page : 2584   Edition : 37,
  ►    Mechanism of Drug Drug Interaction :  ,
Ref :-   Book :    Page :    Edition : ,


  ►  Mechanism of Action :   ,
Ref :-   Book :    Page :    Edition : ,
 ►   

Dietary Products that produce same effect as  Nitisinone

  •    Soyabean , compounds that act on the same pathway as Nitisinone





►   Route of Elimination :   NA


►    Plasma Half-life :   Min value :-   NA    Max value :-   NA


►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA