Medicine :   
Norgestrel is a Medicine belongs to Nortestosterone derivatives group whose properties about Brand can be referenced from   Book : Goodman    Page : 1187   Edition : 12,

  ►   Brandname : Norplant Ii,Jadelle

  ►  Doseform : Tablet with nf  ,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page :    Edition : ,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Goodman    Page : 1186   Edition : 12,

  ►  Indication/uses : hormonal contraceptive,
Reference :-   Book : Goodman    Page : 1186   Edition : 12,
Dosing of Medicine differ in Adult & Pediatrics ↓


► Norgestrel medicine for Adults :

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage   Frequency   Additional Info
1 hormonal contraceptive Oral 0.3 0.5 mg Pill

Ref :-  Book : Goodman    Page : 1186   Edition : 12,




For Pediatric :
S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage   Additional Info  

Ref :- Book :
Precaution :- If a Patient is using 'Norgestrel' drug in  Contraception  disease, then Please Contraindication: Venous thromboembolism breast cancer, un-diagnosed vaginal bleeding. .

►  Side Effect : gastrointestinal disturbance, changes in appetite, changes in weight, fluid retention, oedema, acne, Chloasma, allergic skin rashes, Urticaria, mental depression, breast changes, Gynaecomastia, changes in libido, hair loss, Hirsutism, fatigue, drowsiness, insomnia, fever, headache, premenstrual syndrome-like symptoms, altered menstrual cycles, irregular menstrual bleeding,
Ref :-   Book : Martindale    Page : 2333   Edition : 37,

►  Interaction : Carbamazapine , Griseofulvin , Phenobarbital , Phenytoin , Rifampicin , Cyclosporine ,
Ref :-   Book : Basic & Clinical pharmacology    Page : 2333   Edition : 37,


►  Contraindication : , cardiac impairment, renal impairment, asthma, Epilepsy, migraine,
Ref :-   Book : Martindale    Page : 2333   Edition : 37,
  ►    Mechanism of Drug Drug Interaction :  Aminoglutethimide markedly reduces the plasma concentrations of medroxyprogesterone acetate and megestrol, possibly through a hepatic enzyme-inducing effect; an increase in progestogen dose is likely to be required,
Ref :-   Book : Martindale    Page : 2333   Edition : 37,


  ►  Mechanism of Action :   Suppress GnRH, LH, and FSH secretion and follicular development, thereby inhibiting ovulation; secondary mechanism of pregnancy prevention include alterations in tubal peristalsis, endometrial receptivity and cervical mucus secretions, which together prevent the proper transport of both egg and sperm ,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 523   Edition : 3,
 ►   

Dietary Products that produce same effect as  Norgestrel






►   Route of Elimination :   Renal,
Ref :-   Book : Goodman    Page : 1183   Edition : 12,


►    Plasma Half-life :   Min value :-   16 hours,    Max value :-   NA
Ref :-   Book : Basic & Clinical pharmacology    Page : 1183   Edition : 12,


►    Peak Plasma Concentration :   Min value :-   nf,    Max value :-   NA
Ref :-   Book :    Page :    Edition : ,